الرئيسيةبحث

ترانسفيراز

في الكيمياء الحيوية : الترانسفيراز أحد أنواع الإنزيمات التي تحفز نقل زمرة وظيفية (مثل ميتيل أو فوسفات ) من جزيئة (تدعى المناح ) إلى جزيئة تدعى القابل أو المتقبل . مثلا الإنزيم الذي يتوسط هذا التفاعل يمكن أن يكون ترانسفيرازا :

A–X + B → A + B–X

في هذا المثال ، A يمكن أن يكون المانح ، and B يمكن أن يكون القابل . المانح غالبا ما يكون مرافق إنزيم coenzyme .


بروتينات : إنزيمات
مواضيع موقع فعال - موقع رابط - إنزيم كامل تحفيزيا - مرافق إنزيم - عامل مرافق - عدد EC - تحفيز إنزيمي - حركيات الإنزيم - مثبط إنزيمي - لطخة لاينويفر-بورك - حركيات ميكايليس-مينتن
أنماط EC1 أوكسيدوريدوكتاز/قائمة - EC2 ترانسفيراز/قائمة - EC3 هيدرولاز/قائمة - EC4 لياز/قائمة - EC5 إيزوميراز/قائمة - EC6 ليغاز/قائمة
Transferase: one carbon transferases (EC 2.1)
2.1.1 - Methyltransferases 5-hydroxyindole-O-methyltransferase/Acetylserotonin O-methyltransferase - Betaine-homocysteine methyltransferase - Catechol-O-methyl transferase - Histamine N-methyltransferase - Homocysteine methyltransferase - 5-Methyltetrahydrofolate-homocysteine methyltransferase - Phosphatidyl ethanolamine methyltransferase - Phenylethanolamine N-methyltransferase - DNMT3B - Histone methyltransferase - Thymidylate synthase - DNA methyltransferase
2.1.2 - Hydroxy methyl-, Formyl- and Related Transferases Serine hydroxymethyltransferase - Phosphoribosylglycinamide formyltransferase - Inosine monophosphate synthase - Glutamate formimidoyltransferase - Aminomethyltransferase
2.1.3 - Carboxy- and Carbamoyl transferases Ornithine transcarbamylase
2.1.4 - Amidino transferases Arginine:glycine amidinotransferase
Aldehyde-ketone transferases (EC 2.2)
Acetolactate synthase - Transaldolase - Transketolase
Transferases: acyltransferases (EC 2.3)
2.3.1: other than amino-acyl groups (mostly acetyltransferases) N-Acetylglutamate synthase - Choline acetyltransferase - Acetyl-Coenzyme A acetyltransferase - Dihydrolipoyl transacetylase - Acetyl-CoA C-acyltransferase - Beta-galactoside transacetylase - Carnitine O-palmitoyltransferase (CPT1, CPT2) - Acyltransferase like 2 - Chloramphenicol acetyltransferase - Aminolevulinic acid synthase - Beta-ketoacyl-ACP synthase - Glyceronephosphate O-acyltransferase - Lecithin-cholesterol acyltransferase - Histone acetyltransferase (P300/CBP) - Serotonin N-acetyl transferase
2.3.2 - Aminoacyltransferases Gamma glutamyl transpeptidase - Peptidyl transferase - Transglutaminase (Tissue transglutaminase, Keratinocyte transglutaminase, Factor XIII)
2.3.3 - converted into alkyl on transfer Citrate synthase - ATP citrate lyase - HMG-CoA synthase
Transferases: glycosyltransferases (EC 2.4)
2.4.1 - Hexosyltransferases Glucosyltransferase (Phosphorylase/Starch phosphorylase/Glycogen phosphorylase/Myophosphorylase, Glycogen branching enzyme, Glycogen synthase, Debranching enzyme) - Galactosyltransferase (B-N-acetylglucosaminyl-glycopeptide b-1,4-galactosyltransferase) - Glucuronosyltransferase (UGT1A1, UGT2B7) - Fucosyltransferase (POFUT1, POFUT2)
2.4.2 - Pentosyltransferases Purine nucleoside phosphorylase - Adenine phosphoribosyltransferase - Hypoxanthine-guanine phosphoribosyltransferase - Uracil phosphoribosyltransferase - Amidophosphoribosyltransferase - ADP Ribose (Cholera toxin, Diphtheria toxin, Pertussis toxin, Poly ADP ribose polymerase)
Alkyl and aryl transferases (EC 2.5)
Dimethylallyltranstransferase - Thiaminase I - Methionine adenosyltransferase - Riboflavin synthase - Dihydropteroate synthetase - Spermidine synthase - Glutathione S-transferase - Farnesyl-diphosphate farnesyltransferase - Alkylglycerone phosphate synthase - Farnesyltransferase - Geranylgeranyltransferase type 1 - Porphobilinogen deaminase
Transferase: transaminases (EC 2.6)
Aspartate transaminase - Alanine transaminase - Tyrosine aminotransferase - Ornithine aminotransferase - Branched chain aminotransferase
Phosphotransferases/kinases (EC 2.7)
2.7.1 - OH acceptor Hexo- - Gluco- - Hepatic fructo- - Galacto- - Phosphofructo- (1, 2) - Thymidine - Glycerol - Pantothenate - Mevalonate - Pyruvate - Deoxycytidine - PFP - Diacylglycerol - Bruton's tyrosine - Phosphoinositide 3 (Class I PI 3, Class II PI 3) - Sphingosine
2.7.2 - COOH acceptor Phosphoglycerate - Aspartate
2.7.3 - N acceptor Creatine
2.7.4 - PO4 acceptor Phosphomevalonate - Adenylate - Nucleoside-diphosphate
2.7.6 - P2O7 Ribose-phosphate diphosphokinase - Thiamine pyrophosphokinase
2.7.7 - nucleotidyl- Integrase - PNPase - Polymerase - UDP-glucose pyrophosphorylase - Galactose-1-phosphate uridylyltransferase -Terminal deoxynucleotidyl transferase - RNA replicase - Reverse transcriptase (Telomerase) - Transposase
2.7.8 - other phos. N-acetylglucosamine-1-phosphate transferase
2.7.10-11 - protein Tyrosine - Serine/threonine-specific
Sulfur-containing group transferases (EC 2.8)
Alcohol sulfotransferase - Tyrosylprotein sulfotransferase